‘Born to be bad’ or ‘Born to be Benign:’ Testing Cells for Esophageal Cancer Risk

Cancer Testing - American Health Council

“Genetically analysing lesions in the food pipe could provide an early and accurate test for esophageal cancer, according to research led by Queen Mary University of London (QMUL), Academic Medical Center in Amsterdam and Arizona State University. The study, published in Nature Communications, shows that some cells that are ‘born to be bad’ could be identified early on, preventing the need for repeated endoscopies.”

Barrett’s Esophagus is a common condition that affects an estimated 1.5 million people in the UK alone, although many are undiagnosed. This condition involves normal cells in the esophagus (food pipe) being replaced by an unusual cell type called Barrett’s Esophagus, and is thought to be a consequence of chronic reflux (heartburn).

People with Barrett’s have an increased risk of developing esophageal cancer — a cancer that has a five year survival of 15 per cent. Although the overall lifetime risk of developing esophageal cancer in people with Barrett’s is significant, most Barrett’s patients will not develop cancer in their lifetime. It is the unfortunate few who will develop an aggressive cancer.”

Read the full article: ‘Born to be bad’ or ‘born to be benign:’ Testing cells for esophageal cancer risk