You are here: Home / Procedures & Technology / Why Lab-Made Stem Cells Might Fail: Errors in DNA Folding
“Induced pluripotent stem cells hold promise for regenerative medicine because they can, in theory, turn into any type of tissue and because they are made from a patient’s own adult cells, guaranteeing compatibility. However, the technique that turns adult cells into these iPS cells is not foolproof; after reverting to their pluripotent state, these cells don’t always correctly differentiate back into adult cells.”
“Researchers from the University of Pennsylvania have now discovered one of the reasons why: the reversion process does not always fully capture the way a cell’s genome is folded up inside its nucleus. This folding configuration directly influences gene expression and therefore the functionality of the cell.”
Read the full article: Why lab-made stem cells might fail: Errors in DNA folding
Recent Posts
- The American Health Council Appoints Dr. James Bashkin, D.Phil. to the Physician Board March 31, 2020
- The American Health Council Appoints Dr. Robert W. Letton, MD to the Physician Board March 19, 2020
- The American Health Council Appoints Dr. Akwasi Adjei to the Industry Board January 17, 2020
- The American Health Council Appoints Dr. Nelson Leung to the Physician Board January 17, 2020
- The American Health Council Appoints Ms. Karie Soost to the Physician Board January 17, 2020
- The American Health Council Appoints Mr. Gregory King to the Industry Board January 17, 2020
